导航菜单
基本情况
2021年博士毕业于四川大学华西公共卫生学院营养与食品卫生学系,军科院环境医学与作业医学研究所联合培养1年。从事营养与健康教学、科研工作,擅长肠道菌群与疾病、功能性益生菌筛选和转化研究等。近年主持/参与国家级、省部级项目10余项,发表学术论文40余篇,授权发明专利2项,发明公开15项。获得2023年度四川省科学技术进步奖三等奖、2025年度教育部高等学校科学研究优秀成果奖二等奖。联系方式:ruyuecheng1993@163.com
工作经历
教育经历:
(1) 2016-09 至 2021-06, 四川大学, 营养与食品卫生学, 博士
(2) 2017-12 至 2018-08, 军事科学院军事医学研究院环境医学与作业医学研究所, 营养与认知, 联合培养博士
(3) 2012-09 至 2016-06, 四川大学, 医学技术(医学营养方向), 学士
工作经历:
(1) 2024/09-至今 四川大学,华西公共卫生学院营养与食品卫生学系,副教授
(2) 2021/10-2024-09 四川大学,华西公共卫生学院营养与食品卫生学系,助理研究员
研究方向(含承担课题)
生命早期微生态与母婴健康的关系;肠-脑轴与神经发育障碍/神经退行性疾病/情绪障碍的关系;功能性益生菌筛选及转化研究。
科研成果
近五年主持和参与的科研项目:
(1)国家自然科学基金青年基金项目,2023-01-01至2025-12-31,30万元,在研,主持
(2)河北省自然科学基金生物农业联合基金重点项目,2023-10-01至2025-12-31,50万元,在研,子课题主持
(3)四川省自然科学基金青年基金项目,2024-10-01至2025-12-31,10万元,在研,主持
(4)四川省卫生健康委员会科技项目(青年苗圃项目),2024-11-01至2026-10-31,10万元,在研,主持
(5)中国营养学会营养科研基金,2023-01-01至2023-12-31,20万元,结题,主持
(6)BINC“母婴营养与护理研究基金”,2023-10-01至2026-12-30,30万元,在研,主持
(7)石家庄市科学技术局,石家庄市重大科技计划项目,2024-03-1至2026-12-31,100万元,在研,参与
(8)国家卫生健康委员会,癌症、心脑血管、呼吸和代谢性疾病防治研究国家科技重大专项2024年度定向项目,2024.12-2028.11,3000万,在研,参与
(9)国家自然科学基金委员会,面上项目,2022-01-01 至 2025-12-31,55万元,在研,参与
(10)国家自然科学基金委员会,面上项目,55万元,结题,参与
(11)国家自然科学基金委员会,区域创新发展联合基金,2023-01-01至2026-12-31,255万元,在研,参与
(12)黑龙江省科学技术厅,首批“揭榜挂帅”科技攻关项目,2021-08-01 至 2024-07-31,100万元,结题,子课题参与
(13)黑龙江省科学技术厅,首批“揭榜挂帅”科技攻关项目,2021-08-01 至 2024-07-31,60万元,结题,子课题参与
科研奖励:
(1)2023年度四川省科学技术进步奖三等奖
(2)2025年度教育部高等学校科学研究优秀成果奖二等奖
著作论文
近五年代表性论著:
[1]Li J, Wang Y, Wu S, Zhou Z, Jia W, Shen X, Li Y, He F*, Cheng R*. Postbiotics Made From Selected Lactic Acid Bacteria Improves Chronic Restraint Stress-Induced Anhedonia and Sleep Disorders. Mol Nutr Food Res. 2025;69(8):e70005.
[2]Luo Y, Li J, Wu S, Jia W, Zhou Z, Liu M, Jiang F, Huang T, Shen X, Li Y, He F*, Cheng R*. Oral supplementation with Bifidobacterium longum ssp. infantis and 2'-fucosyllactose revives gut microbiota perturbation and intestinal and immune developmental delay following early-life antibiotic challenge in BALB/c mice. J Dairy Sci. 2025;108(1):101-118
[3] Yin Z, Wang Y, Feng X, Liu C, Guan X, Liu S, Long Z, Miao Z, He F, Cheng R*, Han Y*, Li K*. Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 promote infected wound healing via regulation of the wound microenvironment. Microb Biotechnol. 2024;17(10):e70031.
[4] Li J, Zhao J, Ze X, Li L, Li Y, Zhou Z, Wu S, Jia W, Liu M, Li Y, Shen X, He F*, Cheng R*. Lacticaseibacillus paracasei 207-27 alters the microbiota-gut-brain axis to improve wearable device-measured sleep duration in healthy adults: a randomized, double-blind, placebo-controlled trial. Food Funct. 2024;15(21):10732-10745.
[5] Zhang Y, Wang Y, Zhou Z, Yang Y, Zhao J, Kang X, Li Z, Shen X, He F*, Cheng R*. Live and Heat-Inactivated Streptococcus thermophilus MN-ZLW-002 Mediate the Gut–Brain Axis, Alleviating Cognitive Dysfunction in APP/PS1 Mice. Nutrients. 2024; 16(6):844.
[6]Han Y, Yin Z#, Wang Y, Jiang Y, Chen J, Miao Z, He F, Cheng R*, Tan L*, Li K*. Photopolymerizable and Antibacterial Hydrogels Loaded with Metabolites from Lacticaseibacillus rhamnosus GG for Infected Wound Healing. Biomacromolecules. 2024;25(4):2587-2596.
[7] Wu S, Jia W, He H, Yin J, Xu H, He C, Zhang Q, Peng Y, Cheng R*. A New Dietary Fiber Can Enhance Satiety and Reduce Postprandial Blood Glucose in Healthy Adults: A Randomized Cross-Over Trial. Nutrients. 2023; 15(21):4569.
[8] Luo Y, Zhang Y, Yang Y, Wu S, Zhao J, Li Y, Kang X, Li Z, Chen J, Shen X, He F*, Cheng R*. Bifidobacterium infantis and 2'-Fucosyllactose supplementation in early life may have potential long-term benefits on gut microbiota, intestinal development, and immune function in mice. J Dairy Sci. 2023;106(11):7461-7476.
[9] Yang Y, Li J, Zhou Z, Wu S, Zhao J, Jia W, Liu M, Shen X, He F, Cheng R*. Gut Microbiota Perturbation in Early Life Could Influence Pediatric Blood Pressure Regulation in a Sex-Dependent Manner in Juvenile Rats. Nutrients. 2023; 15(12):2661.
[10] Cheng R, Zhang Y, Yang Y, Ren L, Li J, Wang Y, Shen X*, He F*. Maternal gestational Bifidobacterium bifidum TMC3115 treatment shapes construction of offspring gut microbiota and development of immune system and induces immune tlerance to food allergen. Front Cell Infect Microbiol. 2022;12:1045109.
[11] Wu S, Ren L, Li J, Shen X, Zhou Q, Miao Z, Jia W, He F*, Cheng R*. Breastfeeding might partially contribute to gut microbiota construction and stabilization of propionate metabolism in cesarean-section infants. Eur J Nutr.2023;62(2):615-631.
[12] Miao Z, Wang J, Shen X, Zhou Q, Luo Y, Liang H, Wang S, Qi S, Cheng R*, He F*. Long-term use of Lacticaseibacillus paracasei N1115 from early life alleviates high-fat-diet-induced obesity and dysmetabolism in mice. Benef Microbes. 2022;13(5):407-416.
[13] Li J, Pu F, Peng C, Wang Y, Zhang Y, Wu S, Wang S, Shen X, Li Y, Cheng R*, He F*. Antibiotic cocktail-induced gut microbiota depletion in different stages could cause host cognitive impairment and emotional disorders in adulthood in different manners. Neurobiol Dis. 2022;170:105757.
[14] Jin J#, Cheng R#, Ren Y, Shen X, Wang J, Xue Y, Zhang H, Jia X, Li T, He F*, Tian H*. Distinctive Gut Microbiota in Patients with Overweight and Obesity with Dyslipidemia and its Responses to Long-term Orlistat and Ezetimibe Intervention: A Randomized Controlled Open-label Trial. Front Pharmacol. 2021;12:732541.
[15] Cheng R, Liang H, Zhang Y, Guo J, Miao Z, Shen X, Chen G, Cheng G, Li M*, He F*. Contributions of Lactobacillus plantarum PC170 administration on the recovery of gut microbiota after short-term ceftriaxone exposure in mice. Benef Microbes. 2020;11(5):489-509.
[16] Cheng R, Xu T, Zhang Y, Wang F, Zhao L, Jiang Y*, He F*. Lactobacillus rhamnosus GG and Bifidobacterium bifidum TMC3115 Can Affect Development of Hippocampal Neurons Cultured In Vitro in a Strain-Dependent Manner. Probiotics Antimicrob Proteins. 2020;12(2):589-599.
学术兼职
乳品营养与功能四川省重点实验室固定成员