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程如越

博士 助理研究员 硕士研究生导师
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基本情况

2021年毕业于四川大学华西公共卫生学院营养与食品卫生学系,军科院环境医学与作业医学研究所联合培养1年。从事营养与健康教学、科研工作,擅长肠道菌群与疾病、功能益生菌筛选和转化研究等,发表学术论文30余篇,主持/参与国家级、省部级项目10余项。联系方式:ruyuecheng1993@163.com

工作经历

2021/10-至今 四川大学,华西公共卫生学院营养与食品卫生学系,助理研究员

研究方向(含承担课题)

肠道菌群与疾病、功能益生菌筛选与转化

科研成果

主持和参与的科研项目

1)国家自然科学基金青年基金项目,82204037,生命早期肠道菌群构建与儿童注意缺陷多动障碍的关系及机制研究,2023-01-01至2025-12-31,30万元,在研,主持

2)河北省自然科学基金生物农业联合基金重点项目,C2023106008,HMOs协同益生菌促进生命早期肠道菌群构建和脑发育的作用及机制研究,2023-10-01至2025-12-31,50万元,在研,子课题主持

3)四川省自然科学基金青年基金项目,24NSFSC3072,具有调节情绪功能的母乳来源“精神益生菌”的开发研究,2024-10-01至2025-12-31,10万元,在研,主持

4)中国博士后科学基金第71批面上资助,2022M712228,生命早期肠道菌群对过敏性疾病和注意缺陷多动障碍相互关联的影响及机制研究,2023-01-01至2024-12-31,8万元,在研,主持

5)四川省博士后科研项目特别资助,TB2022046,乳酸菌和芽孢杆菌青贮复合菌剂的开发研究,2023-01-01至2024-12-31,8万元,在研,主持

6)中国营养学会营养科研基金,CNS-Feihe2022-12,母乳微生物和低聚糖对婴幼儿肠道菌群构建和神经发育的影响,2023-01-01至2023-12-31,20万元,在研,主持

7)BINC“母婴营养与护理研究基金”,2023BINCMCF38,健康婴儿肠道来源双歧杆菌的筛选及其促进神经发育的菌株特异性作用及机制,2023-10-01至2026-12-30,30万元,在研,主持

8)四川大学博士后交叉学科创新启动基金培育项目,JCXK2231,缓释后生元可注射HA水凝胶的构建及其改善肥胖的作用及机制研究,2023-01-01至2024-12-31,10万元,在研,主持

9)四川大学专职博士后研发基金项目,2022SCU12026,生命早期肠道菌群对宿主幼年期和成年期注意缺陷多动障碍的影响及机制研究,2022-01-01 至 2023-12-31,15万元,在研,主持

10)国家自然科学基金委员会,面上项目,82173512,摄入不同类型乳制品对端粒长度的影响及机制研究,2022-01-01 至 2025-12-31,55万元,在研,参与

11)国家自然科学基金委员会,面上项目,81973042,儿童过敏性疾病与肥胖的关系及机制研究:生命早期肠道菌群的关键作用,2020-01-01 至 2023-12-31,55万元,在研,参与

12)国家自然科学基金委员会,区域创新发展联合基金,U22A20334,假饲辅助肠内营养调控创伤炎性反应的作用与机制研究2023-01-01至2026-12-31,255万元,在研,参与

13)黑龙江省科学技术厅,首批“揭榜挂帅”科技攻关项目,2021ZXJ03B01-2,玉米秸秆高效厌氧发酵菌种选育,2021-08-01 至 2024-07-31,100万元,在研,子课题参与

14)黑龙江省科学技术厅,首批“揭榜挂帅”科技攻关项目,2021ZXJ03B05,沼渣、沼液高值化应用关键技术研究与产业化,2021-08-01 至 2024-07-31,60万元,在研,子课题参与

著作论文

[1] Wu S#, Jia W, He H, Yin J, Xu H, He C, Zhang Q, Peng Y, Cheng R*. A New Dietary Fiber Can Enhance Satiety and Reduce Postprandial Blood Glucose in Healthy Adults: A Randomized Cross-Over Trial. Nutrients. 2023; 15(21):4569.

[2] Luo Y#, Zhang Y, Yang Y, Wu S, Zhao J, Li Y, Kang X, Li Z, Chen J, Shen X, He F*, Cheng R*. Bifidobacterium infantis and 2'-Fucosyllactose supplementation in early life may have potential long-term benefits on gut microbiota, intestinal development, and immune function in mice. J Dairy Sci. 2023;106(11):7461-7476.

[3] Yang Y#, Li J, Zhou Z, Wu S, Zhao J, Jia W, Liu M, Shen X, He F, Cheng R*. Gut Microbiota Perturbation in Early Life Could Influence Pediatric Blood Pressure Regulation in a Sex-Dependent Manner in Juvenile Rats. Nutrients. 2023; 15(12):2661.

[4] Cheng R#, Zhang Y, Yang Y, Ren L, Li J, Wang Y, Shen X*, He F*. Maternal gestational Bififidobacterium bififidum TMC3115 treatment shapes construction of offspring gut microbiota and development of immune system and induces immune tolerance to food allergen. Front Cell Infect Microbiol. 2022;12:1045109.

[5] Wu S#, Ren L#, Li J, Shen X, Zhou Q, Miao Z, Jia W, He F*, Cheng R*. Breastfeeding might partially contribute to gut microbiota construction and stabilization of propionate metabolism in cesarean-section infants. Eur J Nutr.2023;62(2):615-631.

[6] Miao ZH#, Wang JN, Shen X, Zhou QQ, Luo YT, Liang HJ, Wang SJ, Qi SH, Cheng RY*, He F*. Long-term use of Lacticaseibacillus paracasei N1115 from early life alleviates high-fat-diet-induced obesity and dysmetabolism in mice. Benef Microbes. 2022;13(5):407-416.

[7] Luo Y#, Cheng R#, Liang H, Miao Z, Wang J, Zhou Q, Chen J, He F*, Shen X*. Influence of high-fat diet on host animal health via bile acid metabolism and benefits of oral-fed Streptococcus thermophilus MN-ZLW-002. Exp Anim. 2022;71(4):468-480.

[8] Li J#, Pu F#, Peng C, Wang Y, Zhang Y, Wu S, Wang S, Shen X, Li Y, Cheng R*, He F*. Antibiotic cocktail-induced gut microbiota depletion in different stages could cause host cognitive impairment and emotional disorders in adulthood in different manners. Neurobiol Dis. 2022;170:105757.

[9] Jin J#, Cheng R#, Ren Y, Shen X, Wang J, Xue Y, Zhang H, Jia X, Li T, He F*, Tian H*. Distinctive Gut Microbiota in Patients with Overweight and Obesity with Dyslipidemia and its Responses to Long-term Orlistat and Ezetimibe Intervention: A Randomized Controlled Open-label Trial. Front Pharmacol. 2021;12:732541.

[10] Cheng R#, Guo J, Zhang Y, Cheng G, Qian W, Wan C, Li M, Marotta F, Shen X*, He F*. Impacts of ceftriaxone exposure during pregnancy on maternal gut and placental microbiota and its influence on maternal and offspring immunity in mice. Exp Anim. 2021;70(2):203-217.

[11] Cheng R#, Liang H, Zhang Y, Guo J, Miao Z, Shen X, Chen G, Cheng G, Li M*, He F*. Contributions of Lactobacillus plantarum PC170 administration on the recovery of gut microbiota after short-term ceftriaxone exposure in mice. Benef Microbes. 2020;11(5):489-509.

[12] Cheng R#, Xu T, Zhang Y, Wang F, Zhao L, Jiang Y*, He F*. Lactobacillus rhamnosus GG and Bifidobacterium bifidum TMC3115 Can Affect Development of Hippocampal Neurons Cultured In Vitro in a Strain-Dependent Manner. Probiotics Antimicrob Proteins. 2020;12(2):589-599. 扩展版ESI高被引论文

[13] Cheng R#, Guo J, Pu F, Wan C, Shi L, Li H, Yang Y, Huang C, Li M*, He F*. Loading ceftriaxone, vancomycin, and Bifidobacteria bifidum TMC3115 to neonatal mice could differently and consequently affect intestinal microbiota and immunity in adulthood. Sci Rep. 2019;9(1):3254.

[14] Cheng RY#, Yao JR#, Wan Q, Guo JW, Pu FF, Shi L, Hu W, Yang YH, Li L, Li M*, He F*. Oral administration of Bifidobacterium bifidum TMC3115 to neonatal mice may alleviate IgE-mediated allergic risk in adulthood. Benef Microbes. 2018;9(5):815-828.

[15] Cheng RY#, Li M, Li SS, He M, Yu XH, Shi L, He F*. Vancomycin and ceftriaxone can damage intestinal microbiota and affect the development of the intestinal tract and immune system to different degrees in neonatal mice. Pathog Dis. 2017;75(8). 

学术兼职

四川省营养学会老年营养分会委员

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