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王正陆

博士 研究员 硕士研究生导师
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基本情况

2019年毕业于北京大学城市与环境学院环境地理学专业获得理学博士学位。主要从事环境毒理学,新环境污染物与人群健康风险评估,污水流行病学,及环境流行病学方向的研究工作,在Water Research,Journal of Hazardous Materials 等行业内顶级期刊发表SCI论文40余篇, 其中第一和通讯作者13篇,积累影响因子大于300,担任多本国际杂志的编委,客座编委及审稿人。

个人主页:https://www.researchgate.net/profile/Wang-Zhenglu

工作经历

2019/07-2022/10 河海大学  海洋学院  海洋生物系 讲师(硕导)
2022/11-至今 四川大学  华西公共卫生学院  劳动卫生与环境卫生学系  特聘副研究员(硕导)

研究方向(含承担课题)

环境新污染物的复合毒性研究:关注抗抑郁药物,全氟化合物与环境颗粒物(包括大气细颗粒物和海洋微塑料)的协同污染及复合毒性机制;室内空气暴露致老年人群认知早衰的内在机制;全氟化合物与神经退行性疾病的流行病关联及机制研究。

科研成果

主持科研项目

1. 国家自然科学基金青年基金项目, 42007370, 环境浓度下甲基苯丙胺和氯胺酮的联合神经毒性及机制研究, 2021/01-2023/12, 负责人;

2. 四川省自然科学基金面上项目, 24NSFSC0653, 基于“肠-脑轴”探究竹荪中新烟碱类农药残留的神经内分泌毒性及健康影响, 2024/01-2025/12, 负责人;

3. 农业农村部,国家农产品质量安全风险评估项目,竹荪多风险因子残留评价及复合风险评估, 2023/01-2025/12, 负责人;

4. 四川大学“从0到1”创新研究项目, 基于污水流行病学手段构建病毒性肠道传染病健康预警系统, 2023/01-2025/12, 负责人;

5. 四川大学引进人才启动经费, 2023/01-2025/12, 负责人;

江苏省“双创博士”人才项目, 基于污水流行病学手段监控社区人群健康状况的方法研发, 2021/01-2022/12, 负责人。

著作论文

科研论文

2023

Zhenglu. Wang, Min. Cai, Peng. Du*, Xiqing. Li. Wastewater surveillance for antibiotics and resistance genes in a river catchment: spatiotemporal variations and the main drivers. Water Res. 2023, 121090. B级)

2022

Shuiping.Dai, Zhenglu.Wang*,Ying. Yang, Peng. Du, Xiqing Li. PM2.5 induced weight loss of mice through altering theintestinal microenvironment: Mucus barrier, gut microbiota, and metabolic profiling. J. Hazard. Mater. 2022, 431(4):128653.B级)

Jiana Li, Liqi Zhang, Xiaolong Dang, Lei Su, Khalida Jabeen, Hao Wang, Zhenglu Wang*. Effects of cooking methods onmicroplastics in dried shellfish. Sci Total Environ. 2022, 155787 B级)

2021

Min.Cai, Zhenglu. Wang*,Haotian. Gu, Hui.Dong, Xu.Zhang, Naxin.Cui, Li.Zhou, Guifa.Chen, Guoyan. Zou*. Occurrenceand temporal variation of antibiotics and antibiotic resistance genes in hospital inpatient department wastewater: Impacts ofdaily schedule of inpatients and wastewater treatment process. Chemosphere. 2021, 292, 133405.

Shuiping. Dai, Zhenglu. Wang*, Ying. Yang, Xiqing. Li. Ketamine induction of physiological functions alterations inCaenorhabditis elegans by chronic and multigenerational exposure and corresponding aquatic environmental risk assessment. Chemosphere. 2021, 288, 132486.

Zhenglu. Wang, Shuiping. Dai, Jinze. Wang, Wei. Du*, Lin. Zhu. Assessment on chronic and transgenerationaltoxicity of methamphetamine to Caenorhabditis elegans and associated aquatic risk through toxicity indicator sensitivitydistribution (TISD) analysis. Environ. Pollut. 2021, 288, 117696.

Zhenglu. Wang, Sheng. Han, Zeqiong. Xu, Peng. Du*, Xiqing. Li. Assessment on the adverse effects on different kinds offish induced by methamphetamine during the natural attenuation process based on adverse outcome pathway. Sci Total Environ.2021, 780, 146587. B级)

Yungui. Li, Yuqiong. Wang, Jinze. Wang, Long. Chen, Zhenglu. Wang*, Sheng. Feng, Nan. Lin, Wei. Du*. Quantifyindividual variation of real‐time PM 2.5 exposure in urban Chinese homes based on a novel method. Indoor Air, 2021, 32(8).

2020

Zhenglu. Wang, Kang. Mao, Wei. Du, Min. Cai, Zhaobin. Zhang, Xiqing. Li*. Diluted concentrations of methamphetaminein surface water induce behavior disorder, transgenerational toxicity, and ecosystem-level consequences of fish. Water Res. 2020,184, 116164. B级)

Zhenglu. Wang, Sheng. Han, Min. Cai, Peng. Du, Zhaobin. Zhang, Xiqing. Li*. Environmental behavior ofmethamphetamine and ketamine in aquatic ecosystem: Degradation, bioaccumulation, distribution, and associated shiftin toxicity and bacterial community. Water Res. 2020, 174, 115585. B级)

Zhenglu. Wang, Zeqiong. Xu, Yuexia. Wu, Zhaobin. Zhang, Xiqing. Li*. Impact of ketamine on the behavior andimmune system of adult medaka (Oryzias latipes) at environmentally relevant concentrations and eco-risk assessment in surfacewater. J. Hazard. Mater. 2020, 393, 121577. B级)

2019

Zhenglu. Wang#, Zeqiong. Xu#, Xiqing. Li*. Impacts of methamphetamine and ketamine on C.elegans’ s physiologicalfunctions at environmentally relevant concentrations and eco-risk assessment in surface waters. J. Hazard. Mater. 2019, 363,268-276. B级)

2018

Zhenglu. Wang, Zeqiong. Xu, Xiqing. Li*, Biodegradation of methamphetamine and ketamine in aquatic ecosystemand associated shift in bacterial community, J. Hazard. Mater. 2018, 359 356-364. (B级)

 

专著:

Teratogenicity Testing - Methods and Protocols:Chapter 14. Caenorhabditis elegans as an In Vivo Model Organism to Elucidate Teratogenic Effects. SPRINGER NATURE2024

消毒学检验(第一版)纸质及数字教材,人民卫生出版社(2024),编委

 

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