导航菜单
基本情况
2020年博士毕业于南开大学，导师为程津培院士，目前主要围绕二氧化碳化学、药物活性分子合成、修饰及其抗肿瘤活性研究以及光动力肿瘤治疗这三个重要研究领域开展相关研究，曾先后主持国家自然科学基金委青年科学基金项目、四川省中央引导地方科技发展专项项目、四川省自然科学基金面上项目、四川省科技厅应用基础研究自由探索型项目、四川大学引进人才项目、中国博士后面上项目等多个科研项目，作为课题骨干参与科技部国家重点研发计划“催化科学”重点专项。申请发明专利8项，授权3项，以（共同）第一作者或通讯作者在Chem. Soc. Rev.、Nat. Commun.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Chem、Sci. Bull.、Chin. J. Catal.、Org. Lett.、Org. Chem. Front.等权威学术杂志发表论文22篇。曾获奖项包括安耐吉学术论文奖（2023），加拿大魁北克省政府奖学金（2023），国家公派博士后项目（2022），天津市人民政府奖学金（2013），国家励志奖学金（2014）。
工作经历
2020/07-2023/07四川大学化学学院，博士后，合作导师：余达刚教授。
2023/09-至今，四川大学华西公共卫生学院（华西第四医院），特聘副研究员。
2024/12-至今，麦吉尔大学，访问学者，合作导师：李朝军院士。
招生方向
公共卫生与预防医学；化学。
研究方向(含承担课题)
CO2化学、药物活性分子合成、修饰及其抗肿瘤活性研究、光动力肿瘤治疗。
科研成果
国家自然科学基金委青年科学基金：2022.01-2024.12，主持，已结题。
四川省中央引导地方科技发展专项：2024.09-2025.08，主持，在研。
四川省自然科学基金面上项目：2024.01-2025.12，主持，在研。
四川省科技厅应用基础研究自由探索型：2021.04-2023.03，主持，已结题。
四川大学引进人才项目：2024.01-2026.12，主持，在研。
中国博士后面上项目：2021.07-2023.09，主持，已结题。
四川大学专职博士后基金：2021.01-2022.12，主持，已结题。
科技部国家重点研发计划“催化科学”重点专项，2024.12-2029.11，参与，在研。
著作论文
1. Y.-J. Li,† Y. Ling,† D. Sun,† G. Wu, S.-S. Yue, H.-Y. Yang, H. Zhang, W. Zhang,* M.-M. Zheng,* X.-S. Xue,* S. Guo*, Radical 1,3-Difunctionalization of β,γ-Unsaturated Ketones via Concomitant 1,2-Carbonyl Migration: An Entrance to β-SF5-/β-CF3SF4-Ketones. J. Am. Chem. Soc. 2025, DOI: 10.1021/jacs.5c09085 (†Equal contribution.)
2. G.-M. Cao,† S.-S. Yan,† L. Song,*Y.-X. Jiang, T.-Y. Gao, Z. Chen, W. Zhang*, J.-H. Ye, D.-G. Yu*, Navigating the functionalization of unactivated alkenes via visible-light photocatalysis. Chem. Soc. Rev. 2025, DOI: 10.1039/D5CS00181A
3. W. Zhang*, W.-H. Zhu, J.-D. Yang*, Photoexcited Structural Diversification of Carboxylic Acids with Phosphorus Promoter. Angew. Chem. Int. Ed. 2025, e202500657. (highlight)
4. J.-C. Xu,† J.-P. Yue,† M. Pan, Y.-C. Chen, W. Wang, X. Zhou, W. Zhang*, J.-H. Ye, D.-G. Yu*, Metallaphotoredox-catalyzed alkynylcarboxylation of alkenes with CO2 and alkynes for expedient access to β-alkynyl acids. Nat. Commun. 2025, 16, 1850. (†Equal contribution)
5. J. Xu, H. Xu, Y. Xu, Z.-Q. Peng, W. Zhang*, X. Li*, Chiral phosphoric acid catalyzed asymmetric synthesis of C–N axially chiral uracils with antitumor activity through kinetic resolution strategy. Org. Chem. Front. 2025, DOI: 10.1039/D5QO00144G.
6. Y.-Y Jiang,† Z. Chen,† Y.-X Jiang, W.-J. Zhu, J.-C. Xu, J.-H. Ye, W. Zhang*, D.-G. Yu*, Visible-Light-Driven Thiolate-Catalyzed Carbo-Carboxylation of Alkenes with CO2: Facile Synthesis of Oxindole-3-acetic Acid Derivatives. Chin. J. Chem. 2025, 43, 2341. (†Equal contribution)
7. C. Li,† W. Zhang,† Y, Xu, Y. Su, T.-Y. Gao, J.-H. Ye, L. Song,*D.-G. Yu*, Carboxylation of C(sp2)–H bonds in quinolone derivatives with CO2: facile synthesis of quinolone carboxylic acids. Org. Chem. Front. 2025, DOI: 10.1039/D5QO00491H. (†Equal contribution)
8. S.-R. Zhang,† J.-P. Yue,† L.-F. Wang, Y.-Y. Gui, W. Zhang*, D.-G. Yu, J.-H. Ye*, Dearomative hydroamination of heteroarenes catalyzed by the phenolate photocatalyst. Chem. Commun. 2024, 60, 13083. (†Equal contribution. ChemComm Emerging Investigators themed collection)
9. Z. Huang†, Y. Xu†, W. Lin, Q. Rui, W. Zhang*, X. Li*, Asymmetric synthesis of acyclic N–N axially chiral indole compounds via catalytic N-acylation reaction. Org. Chem. Front. 2024, 11, 5437. (†Equal contribution)
10. Z. Hao, W. Lin, Z.-Q. Yuan, W. Zhang*, X. Li*, Chiral Isothiourea-Catalyzed Acylative Dynamic Kinetic Resolution of 3 Hydroxyphthalides for Enantioselective Synthesis of Phthalidyl Ester. Chin. J. Chem. 2024, 42, 2341.
11. W. Zhang, Z. Chen, Y.-X. Jiang, L.-L. Liao, W. Wang, J.-H. Ye*, D.-G. Yu*, Arylcarboxylation of unactivated alkenes with CO2 via visible-light photoredox catalysis. Nat. Commun. 2023, 14, 3529.
12. W. Zhang, D.-G. Yu*, J.-H. Ye*, Photocatalytic activation of water: a unique way to mimic free hydrogen atoms. Chem 2023, 9, 2375.
13. W. Zhang, H.-T. Luo, J.-D. Yang*, Breakthrough in phosphonylation of alkyl radicals: Alternative access of alkyl phosphonates. Chem 2023, 9, 2735.
14. Y.-Y. Gui,† S.-S. Yan,† W. Wang, L. Chen, W. Zhang*, J.-H. Ye, D.-G. Yu*, Exploring the applications of carbon dioxide radical anion in organic synthesis, Sci. Bull. 2023, 68, 3124. († Equal contribution)
15. Z.-Y. Bo,† S.-S. Yan†, T.-Y. Gao, L. Song, C.-K. Ran, Y. He, W. Zhang*, G.-M. Cao, D.-G. Yu*, Visible-Light Photoredox-Catalyzed Selective Carboxylation of C(sp2)−F Bonds in Polyfluoroarenes with CO2. Chin. J. Catal. 2022, 43, 2388.
16. W. Zhang, X.-X. Xiang, J. Chen, C. Yang, Y.-L. Pan, J.-P. Cheng, Q. Meng*, X. Li*, Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis. Nat. Commun. 2020, 11, 638.
17. Y.-X. Jiang, L. Chen, C.-K. Ran, L. Song, W. Zhang*, L.-L. Liao, D.-G. Yu*, Visible-Light Photoredox-Catalyzed Ring-Opening Carboxylation of Cyclic Oxime Esters with CO2. ChemSusChem 2020, 13, 6312.
18. W. Zhang, C. Yang, Z.-P. Zhang, X. Li*, J.-P. Cheng, Visible-Light-Triggered Cyanoalkylation of para-Quinone Methides and Its Application to the Synthesis of GPR40 Agonists. Org. Lett. 2019, 21, 4137.
19. W. Zhang, H.-L. Zheng, Y. Liu, A. Yu, C. Yang*, X. Li*, J.-P. Cheng, Catalyst-Free Amination of α-Cyanoarylacetates Enabled by Single-Electron Transfer. Org. Chem. Front. 2019, 6, 1900.
20. W. Zhang, Y.-L. Pan, C. Yang, X. Li, B. Wang*, Ring-opening C(sp3)−C coupling of cyclobutanone oxime esters for the preparation of cyanoalkyl containing heterocycles enabled by photocatalysis. Org. Chem. Front. 2019, 6, 2765.
21. W. Zhang,† Y.-L. Pan,† C. Yang, L. Chen, X. Li*, J.-P. Cheng, Metal-Free Direct C–H Cyanoalkylation of Quinoxalin-2(1H)-Ones by Organic Photoredox Catalysis. J. Org. Chem. 2019, 84, 7786. (†Equal contribution)
学术兼职
担任第五届Chin. Chem. Lett.青年编委。